New Launched October 2026

Bloom Her Desire

Botanical support for women's desire and intimate well-being.

Spatikama™ is a botanical nutraceutical for women: a combination of licorice and fenugreek extracts. It supports healthy libido and arousal, natural lubrication and intimate comfort, along with mood and hormonal balance.*

Patent filedUS and India
Trademark filedIn 20 countries
2 human studiesClinical, in women
100% naturalActive ingredients
What Spatikama™ does

Support for desire, comfort and balance.

A woman's desire is shaped by her hormones, her blood flow and her mood, all at once. Spatikama™ combines licorice and fenugreek extracts to support all three.*

  • Desire and arousalSupports healthy libido and sexual arousal.*
  • Blood flow and lubricationSupports healthy genital blood flow and natural lubrication.*
  • Intimate comfortSupports intimate comfort and sexual well-being.*
  • Mood and calmSupports mood, focus and a calmer response to everyday stress.*
  • Hormonal balanceSupports healthy hormonal balance.*

Made foradult women whose desire has dipped with everyday stress, fatigue or the changes that come with age.

Did you know?

Desire is part of her well-being.

Yet it is rarely talked about, and too often put down to stress or simply getting older. Spatikama™ was made for that conversation.

32–43%of women aged 18 to 59 report a lack of interest in sex or decreased desire, the most commonly reported sexual health concern.

Source · National Health and Social Life Survey (NHSLS)

The name

Crystal and desire.

SpatikCrystalpurity · clarity
KamaDesirelove · passion

Together, feminine balance. Spatikama™: the essence of feminine wellness.

What's inside

A combination of licorice and fenugreek extracts.

Each extract brings its own mechanism. Together they deliver a single mechanism of action, the dopamine–estrogen pathway, supporting the signals behind desire.*

  1. 01
    LicoriceGlycyrrhiza glabra

    Estrogen and dopamine signaling. Supports the hormone and brain signals that shape desire, and nervous system health.*

  2. 02
    FenugreekTrigonella foenum-graecum

    Blood flow. Supports nitric oxide for healthy blood flow, and healthy testosterone levels.*

Ginger (Zingiber officinale) is added only as a diluent.

Licorice root and fenugreek seeds on linen
Mechanism of action

The dopamine–estrogen mediated pathway.

Spatikama™ modulates estrogen and dopamine signaling. Follow the signal step by step, or tap any part of the pathway to look closer.Scroll to follow the signal through the cell, step by step.

Spatikama™

Activates estrogen-responsive and dopamine-associated molecular pathways, without upregulating ESR1.

Estrogen (E2)

ESR1 (ER-α)

Not upregulated by Spatikama™

Membrane-associated ERα/ERβ
Cell membrane
ERαClassical genomic signaling
ERβClassical and non-genomic signaling
GPER1G-protein coupled estrogen receptor

ERα signaling protective

  • Protects dopamine neurons in the striatum
  • Regulates D1 and D2 receptor density and sensitivity

ERβ signaling proposed · Glycyrrhiza glabra

  • Maintains dopamine transporter (DAT) binding
  • Linked to the dopamine synthesis pathway

GPER1 signaling proposed

  • Rapid, non-genomic signaling
  • Works with membrane-associated ERα/ERβ
Dopamine biosynthesis

Increased tyrosine hydroxylase (TH) expression

62.5 and 31.25 µg/mL

Increased DRD2 expression

62.5 and 31.25 µg/mL

Tyrosine
L-DOPA
Dopamine
D2 receptor

Dopaminergic signaling

  • Higher threshold for sexual arousal
  • Neuroendocrine regulation
  • Anticipatory drive (libido)
  • Reward response

↑ PS2 (TFF1) expression

62.5 and 31.25 µg/mL

3×

Strong estrogen-responsive activity

Estrogen · nitric oxide · dopamine axis proposed

↑ Nitric oxide synthase (NOS)

Estrogen upregulation

↑ Nitric oxide (NO)

Enhanced dopamine release

Drives sexual motivation

Fenugreek is known to increase nitric oxide production and may contribute to this pathway (correlated with increased estrogen expression in vitro).
What it supports
Neuronal protection and plasticity*
Improved learning and memory*
Enhanced reward response*
Increased sexual motivation and libido*
Overall neuroendocrine balance*
The whole pathway

From one estrogen signal to dopamine.

Press play to follow the signal through the cell, or tap any part of the pathway. Pink markers show findings demonstrated in vitro; dashed outlines show proposed mechanisms.

Step 1 of 6 · The signal

It starts with estrogen signaling.

Spatikama™ activates estrogen-responsive and dopamine-associated molecular pathways. In vitro, it did so without upregulating ESR1, the gene for estrogen receptor alpha (ER-α).

Demonstrated in vitro: no increase in ESR1 (ER-α) expression
Step 2 of 6 · Receptors

Three receptors carry the signal into the cell.

Estrogen acts through ERα (classical genomic signaling), ERβ (classical and non-genomic signaling) and GPER1, a G-protein coupled receptor. ERα signaling protects dopamine neurons; the ERβ route, linked to licorice (Glycyrrhiza glabra), and the GPER1 route are proposed.

Proposed: ERβ signalingProposed: GPER1 signaling
Step 3 of 6 · Dopamine

More of the machinery for dopamine.

Tyrosine hydroxylase (TH) turns tyrosine into L-DOPA on the way to dopamine, which acts on D2 receptors and shapes drive, reward and neuroendocrine regulation. In vitro, Spatikama™ increased TH and DRD2 gene expression at 62.5 and 31.25 µg/mL.

Demonstrated in vitro: ↑ TH expressionDemonstrated in vitro: ↑ DRD2 expression
Step 4 of 6 · Estrogen response

A strong estrogen-responsive signal.

PS2 (TFF1) is a marker of estrogen-responsive activity. In vitro, Spatikama™ raised PS2 (TFF1) expression 3-fold at 62.5 and 31.25 µg/mL, without an increase in ESR1.

Demonstrated in vitro: 3-fold ↑ PS2 (TFF1)
Step 5 of 6 · Nitric oxide

The estrogen, nitric oxide and dopamine axis.

Estrogen upregulates nitric oxide synthase (NOS). More nitric oxide can enhance dopamine release, which drives sexual motivation. Fenugreek is known to increase nitric oxide production and may contribute to this pathway.

Proposed: requires further validation
Step 6 of 6 · What it supports

What the pathway supports.

Together, these signals support neuronal protection and plasticity, learning and memory, the reward response, sexual motivation and libido, and overall neuroendocrine balance.*

Highly researched

Studied in women.

Spatikama™ has been through two human clinical studies, an in-vivo efficacy and safety study, and in-vitro work on how it acts.

Across the two human studies, women reported

  • Improved vaginal lubrication and less discomfort*
  • Calmer emotional responses to stress and less anxiousness*
  • A better overall sense of well-being and comfort*
  • Greater intimate comfort and sexual well-being*

The details are in the product information

  • The full mechanism studyEvery marker and concentration
  • Efficacy and safetyIn vivo
  • Two human clinical studiesIn women
  • Established safetyAcute oral toxicity · OECD 423
  • Vertically integratedFrom the field to the finished extract
  • Full specificationMarkers, particle size and stability
Ask for the product information
Product details

Ready for the format your brand needs.

Spatikama™ is a light brown, free-flowing, water-soluble powder. It can go into capsules, drinks, shots and powder premixes.

Possible formats

  • Capsules400 mg and 600 mg
  • Ready to drink5 g
  • ShotsSingle-serve drinks
  • Powder premixTo mix into drinks
Actives
Licorice (Glycyrrhiza glabra) and fenugreek (Trigonella foenum-graecum) extracts
Diluent
Ginger (Zingiber officinale), added only as a diluent
Extraction
Hydroalcoholic
Appearance
Light brown, free-flowing powder
Solubility in water
Not less than 75% w/w
Full specification
Markers, particle size and stability, in the product information
Spatikama™ for your brand

Be among the first to formulate with it.

  • Request a sample
  • Product information
  • Study summaries
  • Private-label support

Tell us what you need.

The studies and the full specification are shared with brand partners. We reply from info@greenspaceherbs.com.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Spatikama™ is a Greenspace Herbs ingredient; it is not energized and not part of the Quantum Ayurveda™ range. Claims and regulatory suitability should be reviewed for each target market and finished-product application.